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Meclizine dihydrochloride

CAS No. 1104-22-9

Meclizine dihydrochloride ( NSC 28728 )

Catalog No. M10399 CAS No. 1104-22-9

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties.

Purity : >98%(HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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500MG	Get Quote	In Stock
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Biological Information

Product Name

Meclizine dihydrochloride
Note

Research use only, not for human use.
Brief Description

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties.
Description

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.
Synonyms

NSC 28728
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

H1 receptor
Research Area

Neurological Disease
Indication

——

Chemical Information

CAS Number

1104-22-9
Formula Weight

463.87
Molecular Formula

C25H27ClN2·2HCl
Purity

>98%(HPLC)
Solubility

DMSO: 1 mg/mL (2.15 mM)
SMILES

Cl.Cl.CC1=CC(CN2CCN(CC2)C(C2=CC=CC=C2)C2=CC=C(Cl)C=C2)=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.King CT, et al. J Pharmacol Exp Ther, 1965, 147, 391-398.

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