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Home - Products - GPCR/G Protein - Histamine Receptor - Meclizine dihydrochloride

Meclizine dihydrochloride

CAS No. 1104-22-9

Meclizine dihydrochloride ( NSC 28728 )

Catalog No. M10399 CAS No. 1104-22-9

Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Meclizine dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties.
  • Description
    Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.
  • Synonyms
    NSC 28728
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H1 receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1104-22-9
  • Formula Weight
    463.87
  • Molecular Formula
    C25H27ClN2·2HCl
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 1 mg/mL (2.15 mM)
  • SMILES
    Cl.Cl.CC1=CC(CN2CCN(CC2)C(C2=CC=CC=C2)C2=CC=C(Cl)C=C2)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.King CT, et al. J Pharmacol Exp Ther, 1965, 147, 391-398.
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